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Ken Rothman (Boston University) https://simons.berkeley.edu/talks/ken... Theory of Computing and Healthcare Epidemiologic research dates back to at least the 17th century, when a haberdasher in London, John Graunt, used routinely collected data to discover that more males are born than females, and that plague epidemics are not always coincident with the coronation of a new king. In the 19th century, John Snow, considered the father of epidemiology, conducted remarkable studies that famously showed cholera to be spread via fecal-oral transmission. This research did not require computers or data processing technology. Despite the reliance of much of modern day epidemiologic research on sophisticated analytic methods and on adroit combination of electronic data sources, the conduct of epidemiologic research is not fundamentally dependent on technology. Epidemiologists have of course capitalized on the use of digital technology and data storehouses to circumvent the difficulty of collecting vast amounts of data for each new research study. But technology brings with it new problems, which I intend to illustrate.