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A BCI-Based Language Training for Patients with Chronic Aphasia Aphasia refers to an impairment of language abilities mainly due to a left-hemispheric stroke. About 20% of all first stroke patients remain with a persistent, chronic communicative impairment which has a large impact on their quality of life. For the 610,000 first stroke incidents in the US alone, this translates to approx. 122,000 new chronic aphasic patients every year. In the chronic phase, high-intensity language training guided by a speech therapist can lead to improvements, but with a limited generalization to functional communication and moderate effect sizes only. Motivated by the success of recent BCI-supported hand motor training protocols, Michael Tangermann and his team from Albert-Ludwigs-University Freiburg, Germany have implemented and validated a BCI-based closed-loop training protocol for chronic aphasia patients after stroke. Michael Tangermann 1,3, David Hübner 1,3, Simone Denzer, Atieh Bamdadian 4, Sarah Schwarzkopf 2,3, Mariacristina Musso 2,3 1 Brain State Decoding Lab, Dept. Computer Science, Albert-Ludwigs-Universität Freiburg, Germany. 2 Department of Neurology, University Medical Center Freiburg, Germany. 3 Cluster of Excellence BrainLinks-BrainTools, Albert-Ludwigs-Universität Freiburg, Germany. 4 Inovigate, Aeschenvorstadt 55, 4051 Basel, Switzerland.