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A presentation for the Innovations in the Science of Cannabis Conference, May 2021, McMaster University Stephanie Penta explores the complex relationship between problematic cannabis use, emotion dysregulation (ED), and borderline personality disorder (BPD) acuity. Using data from an ongoing study at St. Joseph’s Healthcare Hamilton in collaboration with the Peter Boris Center for Addictions Research at McMaster University, this research highlights how cannabis misuse interacts with specific facets of emotion dysregulation—such as non-acceptance of emotional responses and limited access to emotion regulation strategies—to exacerbate BPD symptoms. The findings suggest that incorporating harm reduction techniques and strategies to reduce cannabis use could significantly improve treatment outcomes for individuals with BPD. The study involved 80 participants from the Borderline Personality Disorder Service, with results showing that higher levels of cannabis misuse and emotion dysregulation correlate with increased BPD acuity. However, when these factors are low, BPD symptoms are less severe. This research underscores the importance of addressing both cannabis use and emotion regulation in BPD treatment programs, offering a new perspective on improving mental health outcomes. Special thanks to the Community Psychiatry Clinic, Peter Boris Center for Addictions Research, and the dedicated students and research assistants who made this study possible. If you’re interested in mental health, addiction research, or the intersection of cannabis use and personality disorders, this presentation is a must-watch! ___________________________________________________ Problematic cannabis use and BPD Emotion dysregulation and borderline personality disorder Cannabis misuse and mental health Borderline personality disorder treatment Cannabis and emotion regulation BPD symptoms and cannabis use Harm reduction for cannabis use St. Joseph’s Healthcare Hamilton research Peter Boris Center for Addictions Research Cannabis and mental illness ___________________________________________________