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Human Brains: Preserving the Brain – Forum on Neurodegenerative Diseases Workshop #10 Inflammation and immunological responses in neurodegenerative diseases German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association 30 September 2022 from 10.00 am to 12.00 pm CEST PROGRAM Adriano Aguzzi, Lessons learned from prion diseases Michael Heneka, Sterile inflammation in neurodegenerative disease Harald Pruess, Anti-neuronal autoantibodies in neurodegenerative dementia ABSTRACT Neurodegenerative diseases as well as other diseases of the nervous system are complex disorders involving both local and systemic mechanisms. Recent research strongly suggests that the immune system is involved in the development of neurodegenerative brain diseases. Both innate and acquired immunity play very important roles from the early stages to disease progression. In this session, speakers will address both fundamental and clinical aspects of the immune response in neurodegenerative diseases.