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Gonorrhea remains one of the more common sexually transmitted infections. In North America, the number of reported cases has generally risen for over ten years, with interruptions in the early days of the COVID-19 pandemic, followed by returns to rising rates of infection. Under the selective pressure of antimicrobial treatment, antimicrobial resistance has risen, which has led to limited options for treatment. Today, we will be discussing antimicrobial resistance in N. gonorrhoeae, including these questions: How accurate is gradient diffusion susceptibility testing when compared to agar-dilution results? Should we use analysis of whole genome sequencing results or agar dilution phenotypic results as the gold-standard for antibiotic susceptibility testing of N. gonorrhoeae? What is the utility of beta-lactamase testing for predicting penicillin susceptibility results in N. gonorrhoeae? Guests: Dr. Tanis Dingle, Clinical Microbiologist at Alberta Precision Laboratories and a Clinical Associate Professor in the Department of Pathology and Laboratory Medicine at the University of Calgary. Dr. Angela Ma., Clinical Microbiologist at Public Health Ontario. This episode of Editors in Conversation is brought to you by the Journal of Clinical Microbiology and hosted by JCM Editor in Chief, Alex McAdam and Dr. Elli Theel. Editors in conversation is supported by the American Society for Microbiology, which publishes JCM. If you are a member of ASM, you can get up to 50% off the publication fees when you publish in JCM or any of the ASM journals. Visit https://journals.asm.org/journal/jcm to read articles and/or submit a manuscript. Follow EIC, Alex McAdam on twitter for JCM updates via / jclinmicro and co-host, Elli Theel at / etheelphd . Subscribe to the podcast at https://asm.org/eic 👍 Subscribe to ASM's YouTube channel at https://goo.gl/mOVHlK ✅ Become a member today at https://asm.org/Membership 🔬 Learn more about the American Society for Microbiology at https://www.asm.org 📱 Join us on social: Facebook: / asmfan Twitter: / asmicrobiology Instagram: / asmicrobiology