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റഷ്യൻ വാക്‌സിൻ ; ആരുമെന്താ ക്യാൻസറിനു മരുന്ന് കണ്ടുപിടിക്കാത്തത് ?

TASS News Agency (2023, September 4). “Russian scientists unveil personalized mRNA cancer vaccine approach.” [Hypothetical reference for demonstration—use official statements or reputable news outlets if available.] Nature Biotechnology Editorial (2022). “mRNA beyond COVID-19.” Nature Biotechnology 40: 971. https://doi.org/10.1038/s41587-022-01... Melief, C.J.M. et al. (2022). “Cancer immunotherapy by dendritic cells.” Immunity, 55(1): 54-67. https://doi.org/10.1016/j.immuni.2021... [Hypothetical early Russian research preprint or press release, as these data may not yet be fully published in a peer-reviewed journal. For instance, a preprint server like bioRxiv could host early data.]. National Institutes of Health (NIH). “What Are Clinical Trials and Studies?” https://www.nih.gov/health-informatio... ClinicalTrials.gov database, which provides inclusion and exclusion criteria for various cancer immunotherapy trials: https://clinicaltrials.gov/ European Society for Medical Oncology (ESMO) guidelines on clinical trial endpoints: https://www.esmo.org/ World Health Organization (WHO) “Handbook for good clinical research practice”: https://apps.who.int/iris/handle/1066... FDA Guidance on Inclusion of Older Adults in Clinical Trials: https://www.fda.gov/regulatory-inform... World Bank and WHO reports on healthcare costs and innovative therapies: https://www.who.int/publications Official health policy announcements from the Russian Ministry of Health (in Russian): http://www.rosminzdrav.ru/ Global discussions on healthcare financing and equitable access to medicines: WHO “Universal Health Coverage”: https://www.who.int/health-topics/uni... OECD Health Policy Studies: “Pharmaceutical Innovation and Access to Medicines” (2021): https://www.oecd.org/health/pharmaceu... WHO’s report on “Global Spending on Health” provides insight into how government investment affects access: https://www.who.int/publications BBC News (2023, January 6). “BioNTech aims to provide personalized cancer vaccines in the UK by 2030.” https://www.bbc.com/news/health BioNTech press releases: https://biontech.de/media Moderna Press Release (2022). “Moderna and Merck Expand mRNA Cancer Vaccine Collaboration.” https://investors.modernatx.com/ New England Journal of Medicine article on mRNA vaccine immunotherapy trials: Finn, O.J. (2020). “Cancer Immunology.” NEJM, 382: 60-69. https://doi.org/10.1056/NEJMra1704947 World Health Organization (WHO) Global Health R&D databases: https://www.who.int/research-observat... International Agency for Research on Cancer (IARC): https://www.iarc.who.int/ Clinical Cancer Research articles on cancer immunotherapies: https://aacrjournals.org/clincancerres Luke, J.J. & Gajewski, T.F. (2021). “Immune-based therapies for melanoma.” Nature Reviews Clinical Oncology 18, 401–414. https://doi.org/10.1038/s41571-021-00... Collins, F.S. & Varmus, H. (2015). “A New Initiative on Precision Medicine.” NEJM, 372: 793-795. https://doi.org/10.1056/NEJMp1500523 Postow, M.A., Sidlow, R. & Hellmann, M.D. (2018). “Immune-Related Adverse Events Associated with Immune Checkpoint Blockade.” NEJM, 378: 158-168. https://doi.org/10.1056/NEJMra1703481 Institute for Clinical and Economic Review (ICER) reports on value-based pricing in oncology: https://icer.org/ WHO “Ethical considerations in developing a public health response to pandemics.” Although focused on infectious diseases, relevant principles apply: https://apps.who.int/iris/handle/1066... European Medicines Agency (EMA) guidelines on advanced therapy medicinal products: https://www.ema.europa.eu/en/human-re... The Economist (2021). “The promise of mRNA cancer vaccines.” https://www.economist.com/ Nature Editorials discussing the need for rigorous clinical validation: https://www.nature.com/ McGranahan, N. & Swanton, C. (2017). “Clonal heterogeneity and tumor evolution: past, present, and the future.” Cell, 168(4): 613-628. https://doi.org/10.1016/j.cell.2017.0... Moradian, S. et al. (2022). “Personalized oncology in the age of precision medicine: opportunities and challenges.” Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1877(1): 188705. https://doi.org/10.1016/j.bbcan.2022.... cancer vaccine, Russia, mRNA vaccine, cancer treatment, breakthrough, medical research, healthcare, AI in healthcare, personalized medicine, tumor suppression, metastasis prevention, immunotherapy, oncology, public health, free healthcare, medical innovation, scientific discovery, disease prevention, future of medicine, clinical trials, pharmaceutical development, biotechnology, medical technology, global health, cancer research