6. Conn’s Syndrome (Primary Hyperaldosteronism) | Internal Medicine скачать в хорошем качестве

6. Conn’s Syndrome (Primary Hyperaldosteronism) | Internal Medicine

Conn’s Syndrome (Primary Hyperaldosteronism) 🧠💥 | Internal Medicine NEET PG, USMLE, FMGE & MBBS 💯 Conn’s Syndrome, also known as Primary Hyperaldosteronism, is a high-yield endocrine disorder caused by autonomous overproduction of aldosterone from the adrenal cortex, most commonly due to an aldosterone-producing adenoma or bilateral adrenal hyperplasia. This excess aldosterone leads to sodium and water retention, resulting in hypertension, and increased excretion of potassium and hydrogen ions, causing hypokalemia and metabolic alkalosis. Clinically, patients present with resistant hypertension, muscle weakness, cramps, fatigue, paresthesias, and in severe cases, cardiac arrhythmias. Screening involves checking the aldosterone-to-renin ratio (ARR), which is elevated in Conn’s Syndrome. Confirmation is done through saline suppression tests, CT imaging of the adrenal glands, and adrenal venous sampling to determine lateralization. Treatment depends on the cause—unilateral adenomas are treated surgically via adrenalectomy, while bilateral hyperplasia is managed medically with mineralocorticoid receptor antagonists like spironolactone or eplerenone. This video explains the pathophysiology, clinical features, diagnostic workup, and treatment strategies using rich visuals, mnemonics, and case-based learning—making it a must-watch for NEET PG, USMLE, FMGE, and MBBS students aiming for conceptual clarity and exam success. #ConnsSyndrome #PrimaryHyperaldosteronism #InternalMedicine #EndocrinologyMadeEasy #NEETPG2025 #USMLEStep2CK #FMGE2025 #Hypertension #Hypokalemia #AdrenalAdenoma #MedicalEducation #DoctorInTheMaking #MBBSLectures #ClinicalMedicine #HighYieldTopics #PathophysiologyExplained #Spironolactone #ExamCracker #AnatomyAndPhysiology #ElectrolyteImbalance