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Tissue Regeneration Using Nature's Way

Dr. Anne George is the University of Illinois at Chicago College of Dentistry’s Allan G. Brodie Endowed Professor, and professor of oral biology, and was selected as a UIC University Scholar in 2018. George has been instrumental in cloning dentin matrix protein genes (DMPs) from the mineralized dentin matrix of animal models, and she is working towards dentists filling cavities with DMP1, which would allow dentin to regenerate. George’s research focuses on regenerative science, biomaterials, bioengineering, and stem cell biology. She is the director of the college’s Brodie Tooth Development Genetics and Regenerative Medicine Research Laboratory. The research of George and her team on the role of the gene Dentin Matrix Protein 1 (DMP1) in bone metabolism could lead to a new way of filling oral caries. They are studying how proteins can regenerate dentin, a calcified tissue of the body that, along with enamel, cementum, and pulp, is one of the four major components of teeth.