Tip-98;Pancreatic Intraductal Papillary Mucinous Neoplasm (IPMN), with Colloid Carcinoma скачать в хорошем качестве

Tip-98;Pancreatic Intraductal Papillary Mucinous Neoplasm (IPMN), with Colloid Carcinoma

Tip-98; Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is a grossly visible, typically less than 5 mm, intraductal epithelial neoplasm of mucin-producing cells, arising in the main pancreatic duct and/or its branches. Gastric-type intraductal papillary mucinous neoplasm; intestinal-type intraductal papillary mucinous neoplasm; pancreaticobiliary-type intraductal papillary mucinous neoplasm. IPMNs can occur anywhere in the main pancreatic duct and/or its branches; however, most are located in the head of the pancreas. Multicentricity is observed in as many as 40% of cases. Main duct-type IPMNs are mostly located in the head of the gland but may occasionally involve the entire main pancreatic duct, including the ampulla of Vater, leading to mucin extrusion from a patulous ampullary orifice into the duodenum. Intestinal-type IPMN is the second most common type in about 20% of cases. It typically occurs in the main duct and is characterized by intestinal-type epithelium that forms villous papillae composed of tall columnar cells with cigar-shaped enlarged nuclei and basophilic cytoplasm with variable amounts of apical mucin. Intestinal-type IPMNs usually reveal HGD. Colloid carcinoma, characterized by infiltrating epithelial elements separated by abundant stromal mucin, arises in association with intestinal-type IPMNs.