Understanding SDTM Exposure Domains: EX vs. EC - Key Differences скачать в хорошем качестве

Understanding SDTM Exposure Domains: EX vs. EC - Key Differences

Let's understand and demystify Exposure domains with simple yet detailed explanation. Here we go !!!! In clinical trials, exposure domain refers to the planned or intended exposure to the drug or treatment being tested, while exposure as collected domain refers to the actual exposure that patients receive during the trial. The exposure domain #EX is typically specified in the study protocol and includes details such as the dose, frequency, and duration of the treatment. This information is used to determine the expected exposure for each patient and to calculate the required sample size for the trial. On the other hand, exposure as collected domain #EC refers to the actual exposure that patients receive during the trial, which may differ from the planned exposure. This can occur due to a variety of reasons, such as missed doses, early discontinuation of the treatment, or non-adherence to the treatment regimen. The difference between the exposure domain and exposure as collected domain can have important implications for the interpretation of clinical trial results. For example, if the actual exposure is lower than the planned exposure, the trial may be underpowered to detect a treatment effect. Conversely, if the actual exposure is higher than the planned exposure, this may increase the risk of adverse events and limit the generalizability of the results to real-world practice. Therefore, it is important for clinical trial investigators to carefully monitor and document exposure as collected in order to accurately interpret the trial results and ensure the safety and efficacy of the treatment being tested. **** Want me to mentor you and help you land a high-paying data analyst job? Join my program here: If you’re new to my channel, my name is Murali Krishna Tenali. I’m a Vice President in the tech industry with over 16 years of experience, specializing in SAS, Python, SQL, Tableau, and R programming. Alongside my corporate role, I’m passionate about mentoring students to excel in their careers by mastering these in-demand skills. Over the years, I’ve worked in industries like banking, healthcare, and clinical domains, applying these skills to solve real-world problems and drive impactful results. Through my mentorship programs, I’ve helped countless students secure high-paying jobs in top-tier companies. Details about upcoming batches, job opportunities and latest updates, join my telegram group 👉 https://t.me/+IiSDd_ocLMU0YTU1 How I Got Here… 19 years ago: I started my journey as a college professor, teaching and inspiring young minds. However, being a professor wasn’t sufficient to pay the bills, so I decided to transition into the tech industry. 17 years ago: I entered the tech industry and worked my way up, gaining hands-on experience in analytics, data science, and software engineering. 12 years ago: I realized the lack of proper guidance for aspiring data analysts and started informally mentoring students. 7 years ago: I began teaching structured courses on SAS and data analytics, equipping students with job-ready skills. Today: I’ve mentored thousands of students, helping them break into leading companies, including top names in banking, pharmaceuticals, and healthcare. My courses focus on simplifying complex concepts, working on real-world projects, and preparing you to excel in industry demands. Why I Do This… I know what it feels like to struggle in your career without the right skills or guidance. I also know how life-changing it can be to finally land a job you love. I’ve seen my students grow into confident professionals, earning six-figure salaries and creating fulfilling careers. If you’re serious about building a thriving career in data analytics, I can guide you every step of the way. Whether you’re starting fresh or looking to advance your skills, I’ll teach you exactly what you need to know to stand out in the job market. Here’s How You Can Get Started: 1. Join my free masterclass to get an in-depth introduction to these skills and career opportunities. 2. Sign up for my mentorship program and learn SAS, Python, SQL, or R with live, hands-on sessions. 3. Join my Telegram group for updates on upcoming batches, free resources, and Zoom sessions. Link 👉 https://t.me/+IiSDd_ocLMU0YTU1 If I could sum up my journey in one sentence, it’s this: “With perseverance, learning, and the right mentorship, you can transform your life and career.” Let’s make that happen together! Murali Krishna Tenali FULL DISCLOSURE: I mentor because I want to see my students succeed and create meaningful careers. I believe in teaching with real-world applications and giving back to the community that has given me so much. Watching my students thrive is my greatest reward. If you’re ready to take the leap, let’s get started. Together, we’ll make your career dreams a reality. Let’s do this!