CD95 DISC Composition and Procaspase-8 Processing Analysis | Protocol Preview скачать в хорошем качестве

CD95 DISC Composition and Procaspase-8 Processing Analysis | Protocol Preview

Watch the Full Video at https://www.jove.com/v/62842/measurin.... Measuring Composition of CD95 Death-Inducing Signaling Complex and Processing of Procaspase-8 in this Complex - a 2 minute Preview of the Experimental Protocol Laura K. Hillert-Richter, Inna N. Lavrik Otto von Guericke University Magdeburg, Translational Inflammation Research, Center of Dynamic Systems; Here, an experimental workflow is presented that enables the detection of caspase-8 processing directly at the death-inducing signaling complex (DISC) and determines the composition of this complex. This methodology has broad applications, from unraveling the molecular mechanisms of cell death pathways to the dynamic modeling of apoptosis networks. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments