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Chris Masterjohn, PhD is the Founder and Scientific Director of the mitochondrial test mito.me. Question: Why zinc deficiency causes resistance to thyroid and sex hormones and vitamins A and D The answer to that is because the, because all of those things carry out their gene expression function by binding to nuclear receptors. And all of the nuclear receptors to DNA using zinc finger motifs. Zinc finger motif means that in the nuclear receptor, there's a zinc ion that coordinates the primary structure of the protein, which is a long string of amino acids into a finger shape. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/master... and use the code QANDA to get 10% off the membership for life. Do You Have Hidden Mitochondrial Dysfunction? Mitochondrial dysfunction is one of the earliest signs of aging and chronic disease—and most people don’t know they have it. Mitome is the first at-home test that measures your cellular energy directly and gives you a personalized roadmap to optimize energy, slow aging, and protect against disease. Find my comprehensive mitochondrial analysis at mito.me DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.