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Most cases are harmless – Over half are due to gas and indigestion, which typically resolve within hours or days. Serious causes exist – Pancreatitis and even heart attack can present with pain in this area, especially in atypical cases. Heart attacks can mimic abdominal pain – About 6 percent of myocardial infarctions show upper left abdominal pain, especially in older adults, women, and diabetics. Gas and constipation dominate – Trapped gas in the splenic flexure and constipation are among the top causes, due to distension and pressure in the colon. Musculoskeletal pain is common – Strain or injury in abdominal or chest muscles can cause pain that worsens with movement or breathing. Gastritis and peptic ulcers – Gastritis causes upper central pain, but sometimes affects the left side. Gastric ulcers can also cause left-sided pain, especially after meals. Splenic causes – Conditions like splenomegaly, infarction, or rupture can cause persistent dull pain that may radiate to the left shoulder. Kidney-related pain – Kidney stones and pyelonephritis on the left side may radiate to the upper abdomen, usually with nausea, flank pain, and urinary symptoms. Pancreatitis can localize to the left – If the tail of the pancreas is inflamed, pain often centers in the left upper quadrant, especially after meals. Quadrant-based assessment helps – Dividing the abdomen into four quadrants is essential for identifying the organ involved and guiding diagnosis. Upper Left Stomach Pain, Upper Left Abdominal Pain, upper left quadrant pain Disclaimer: This information is provided for general knowledge and educational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult with your doctor for any questions or concerns you may have about your health.