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In this forward-looking conversation, Dr. Joseph Mikhael and Dr. Shaji Kumar explore what’s coming next in multiple myeloma: smarter targeted screening for MGUS/smoldering, how we may treat high-risk smoldering earlier, whether CAR T-cell therapy could move upfront (and what that means for stem cell transplant), and how MRD (minimal residual disease) will increasingly guide when to start, stop, or restart therapy. You’ll also hear how AI tools and partnerships are accelerating research, matching patients to trials, and even reducing unnecessary bone marrow biopsies Key Takeaways 0:00 - Introduction Smarter, Targeted Screening Treating Smoldering Myeloma: Delay vs. Eradicate Will CAR T-cell Therapy Replace Transplant? MRD Will Guide More Decisions AI Is Accelerating Research & Care Practical Note for Patients Have a question that needs more personalized support? Call us! We’re here for you. The IMF’s InfoLine is available to answer your myeloma-related questions and concerns. Call us at 1-818-487-7455, email us at [email protected], or schedule your call at a time that works best for you at: https://www.myeloma.org/infoline _______________ Improving Lives | Finding the Cure Founded in 1990, the International Myeloma Foundation (IMF) is the first and largest organization focusing specifically on multiple myeloma. The IMF’s reach extends to more than 525,000 members in 140 countries worldwide. The IMF is dedicated to improving the quality of lives of myeloma patients while working toward prevention and a cure through our four founding principles: Research, Education, Support, and Advocacy. Subscribe to our channel: / imfmyeloma Visit our website at: https://www.myeloma.org Find us online: Facebook: @myeloma | / myeloma X/Twitter: @IMFMyeloma | / imfmyeloma Instagram: @imfmyeloma | / imfmyeloma LinkedIn: / international-myeloma-foundation Support the IMF | Donate Now! https://fundraise.myeloma.org/give/52... Category Nonprofits & Activism License Standard YouTube License The International Myeloma Foundation is committed to accessibility for all. That’s why all English-language videos uploaded to our YouTube channel feature human-transcribed closed captioning. This ensures more accurate captions for viewers who are Deaf or hard of hearing and improves the quality of automatic translations into other languages for our global audience.