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In recent years, new non-combustible products have emerged which have complex implications for public health. Scientists and health professionals struggle with balancing the possible harms of nicotine use for youth alongside the potential that adults who smoke cigarettes might reduce harm by switching to non-combustible forms of nicotine. This talk reviews evidence on the products, use prevalence, health effects, and populations impacted by non-combustible commercial nicotine products in the U.S. Electronic cigarettes will be the primary focus. Other emerging products will also be addressed, including novel flavored commercial nicotine gums, gummies, and pouches. The talk will conclude with a discussion of science-informed policies for regulating non-combustible commercial nicotine products to optimize population health. Adam Leventhal, PhD is Professor of Population and Public Health Sciences and Director of the Institute for Addiction Science at University of Southern California Keck School of Medicine. Learn more about SMART brain training: centerforbrainhealth.org/training/smart To learn more about The Center for BrainHealth®, visit our website: brainhealth.utdallas.edu