Dr Rudy Tanzi: Alzheimer's Authority скачать в хорошем качестве

Dr Rudy Tanzi: Alzheimer's Authority

In this episode of Rappaport Connects, host Sean Horrigan sits down with Dr. Rudy Tanzi, a world-leading neuroscientist and geneticist whose groundbreaking work has shaped our understanding of Alzheimer’s disease and brain aging. Dr. Tanzi is Vice-Chair of Neurology and Director of the Genetics and Aging Research Unit at Massachusetts General Hospital, Co-Director of the McCance Center for Brain Health and the MassGeneral Institute for Neurodegenerative Disease, and the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Early in his career, he co-discovered the first three genes responsible for early-onset familial Alzheimer’s disease—foundational discoveries that helped establish the amyloid hypothesis and transformed neurodegenerative research. In this conversation, Dr. Tanzi discusses the origins of the Cure Alzheimer’s Fund, the revolutionary “Alzheimer’s-in-a-Dish” model developed in his lab, and how this system is accelerating the discovery of promising therapies. He also shares insights into novel drug approaches, including gamma-secretase modulators, combination therapies targeting amyloid, tau, and inflammation, and the biomarkers guiding future clinical breakthroughs. Join us for an in-depth look at the future of Alzheimer’s research, the path toward prevention and treatment, and what a truly successful therapy could look like for patients worldwide. Topics Covered: The founding and mission of the Cure Alzheimer’s Fund Breakthrough discoveries from Alzheimer’s-in-a-Dish Promising drug candidates and therapeutic strategies Biomarkers and early indicators for successful treatments The future of combination therapies and clinical timelines