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Visit www.defymedical.com for more information or to schedule your initial consult now! Transcript: Hormone replacement therapy in female patients is complex and multifactorial and the approach that we take often depends on if a patient is pre-menopausal or post-menopausal, or as we sometimes called peri-menopausal, which just means around menopause, close to menopause. For pre-menopausal patients typically the ovaries are still functioning, they're still producing the sex hormones as we call them, testosterone, estrogen, and progesterone, but sometimes the levels can be deficient. Specially you find testosterone often deficient in pre-menopausal women, and that can cause a disorder we call Hypoactive Sexual Desire Disorder, which is essentially low sex drive for women. Another issue we find in pre-menopausal patients is they can develop estrogen dominance during different parts of their menstrual cycle, typically towards the end of the menstrual cycle. Estrogen dominance is when their estrogen levels are much higher than their progesterone levels can balance with, and that typically creates a picture of essentially PMS, irritability, mood swings, breast tenderness, bloating, all those symptoms that many women are all too familiar with and can often be resolved just by bringing some balance back with the progesterone to offset the estrogen dominance. So in pre-menopausal women typically testosterone, progesterone, and then some of the other hormones we always monitor and manage such as thyroid and adrenals is the approach, but they don't typically need estrogen replacement. Now for post-menopausal women the ovaries have shut down, they're not producing those three sex hormones anymore, testosterone, estrogen, or progesterone, so those patients often need the testosterone and progesterone treatment similar to pre-menopausal women, but they also often need estrogen replacement depending on symptoms. And the three main symptoms we look at for estrogen deficiency in post-menopausal women are night sweats, hot flashes, and vaginal dryness, so if a patient is experiencing any or all of those three symptoms and they're post-menopausal they will likely need estrogen replacement. Again, similar to pre-menopausal patients we also look at other hormones such as thyroid and adrenals and address those if necessary.