Physiologically-Based (PBPK) & Population Pharmacokinetic Modeling in Molecular Radiotherapy скачать в хорошем качестве

Physiologically-Based (PBPK) & Population Pharmacokinetic Modeling in Molecular Radiotherapy

Invited Speaker Dr. Deni Hardiansyah (March 6, 2025); PBPK and PopPK Models in Molecular Radiotherapy (MRT) also known as Radiopharmaceutical Therapy (RPT); Chapter Breakdown: 0:00 Introduction 1:59 General concepts 9:26 Introduction to PBPK Modeling 11:16 Implementation of PBPK in MRT 28:57 Implementation of Population PK in MRT 41:50 Implementation of PBPK+Population PK in MRT 45:45 Conclusions Dr. Hardiansyah is an associate professor at the Physics Department FMIPA, University of Indonesia. Dr. Hardiansyah earned a doctoral degree at Heidelberg University, Germany, with a focus on the implementation of physiologically based pharmacokinetic (PBPK) models to improve individual dosimetry in Molecular Radiotherapy (also known as Radiopharmaceutical Therapy). He has also actively published in the field of molecular/functional imaging. After his PhD, he worked as a postdoc and staff at the College of Pharmacy, University of Kentucky, USA, in the field of pharmaceutical sciences. Overall, he has carried out research in various aspects of nuclear medicine dosimetry, imaging and modeling of drug’s PKPD.