Charcot Bouchard Aneurysm; microaneurysm affects small penetrating arteries of brain скачать в хорошем качестве

Charcot Bouchard Aneurysm; microaneurysm affects small penetrating arteries of brain

Charcot–Bouchard aneurysms are tiny, pathological dilations of small penetrating arteries in the brain, typically less than 300 micrometers in diameter. They’re most commonly found in the lenticulostriate branches of the middle cerebral artery, which supply deep brain structures like the basal ganglia, thalamus, pons, and cerebellum2. 🧠 Pathophysiology Cause: Chronic hypertension is the primary culprit. It weakens the vessel walls through processes like lipohyalinosis, making them prone to rupture. Effect: When these microaneurysms rupture, they cause intracerebral hemorrhage, often leading to hemorrhagic stroke. Law of Laplace: As with other aneurysms, increased wall tension can lead to expansion and rupture. 🧪 Clinical Features Often asymptomatic until rupture Sudden onset of: Headache Nausea and vomiting Seizures Focal neurological deficits (e.g., hemiparesis) Decreased consciousness 🧬 Diagnosis CT or MRI: Used to detect intracerebral hemorrhage CT angiography: Often fails to visualize these microaneurysms due to their small size Histopathology: Sometimes the only definitive way to identify them post-mortem 🧠 Historical Note Named after Jean-Martin Charcot and Charles-Joseph Bouchard, who first described these lesions in the 19th century2. #Aneurysm #aneurysms