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Drs. Ramesh Zacharias and Mahmoud Siyam provide an educational session about the therapeutic applications of medical cannabis for chronic pain. Recorded as a part of the Innovations in the Science of Cannabis Conference, October 2023. In this insightful session, Dr. Ramesh Zacharias, President and CEO of The Chronic Pain Center of Excellence for Canadian Veterans, and Dr. Mahmoud Siyam, a clinical pharmacist specializing in pain management, delve into the complexities of chronic pain and the role of medical cannabis in its treatment. They explore the differences between acute and chronic pain, the endocannabinoid system, and the evidence supporting the use of medical cannabis for conditions like neuropathic pain, fibromyalgia, and chemotherapy-induced nausea. The presentation also covers optimizing routes of administration, including inhalation, ingestion, and topical applications, and shares real-world case studies of patients who have benefited from cannabis-based therapies. Dr. Zacharias and Dr. Siyam provide a comprehensive overview of the major cannabinoids, such as THC and CBD, and their effects on pain modulation, inflammation, and overall well-being. They emphasize the importance of starting with low doses and gradually titrating to find the optimal therapeutic window while minimizing side effects. The session also addresses common concerns, such as drug interactions, tolerance, and the challenges of prescribing cannabis in a clinical setting. Whether you're a healthcare professional or someone exploring cannabis as a treatment option, this presentation offers valuable insights and practical guidance. If you found this video helpful, please give it a thumbs up, share it with others, and subscribe to our channel for more expert-led discussions on pain management and medical cannabis. Don’t forget to leave a comment with your thoughts or questions—we’d love to hear from you! ________________________________________________________ 1 Chronic pain treatment with cannabis 2 Medical cannabis for neuropathic pain 3 THC vs CBD for pain relief 4 Endocannabinoid system explained 5 Cannabis inhalation vs ingestion 6 Case studies on medical cannabis 7 Synthetic cannabinoids like Nabilone 8 Cannabis tolerance and titration 9 Cannabis for fibromyalgia pain 10 Cannabis drug interactions ________________________________________________________ The Michael G. DeGroote Centre for Medicinal Cannabis Research is a multidisciplinary leader in medicinal cannabis research. The Centre is led by the Michael G. DeGroote School of Medicine Initiative for Innovation in Healthcare at McMaster University in Hamilton, Ontario, Canada. This initiative leverages McMaster University’s world-renowned expertise in health research and evidence-based medicine to create a hub for evidence-based data and innovative research. https://cannabisresearch.mcmaster.ca/