Central Caseous Necrosis Feature of Tuberculosis скачать в хорошем качестве

Central Caseous Necrosis Feature of Tuberculosis

Central caseous necrosis is a characteristic feature of tuberculosis (TB) granulomas. Here's what it entails: What is central caseous necrosis? Caseous necrosis refers to a type of tissue death (necrosis) that occurs in the center of a TB granuloma. The affected tissue turns into a soft, cheesy, or caseous material. Features: Central area of necrosis within the granuloma Necrotic material is usually pale yellow or white Surrounding tissue is infiltrated with immune cells (macrophages, lymphocytes) May calcify over time, leaving a permanent scar Importance: Central caseous necrosis is a hallmark of TB granulomas Helps distinguish TB from other granulomatous diseases Indicates a chronic, cell-mediated immune response to Mycobacterium tuberculosis Location: Typically found in lung granulomas, but can also occur in other affected tissues (e.g., lymph nodes, kidneys) Note: Central caseous necrosis is not unique to TB and can be seen in other conditions, such as fungal infections or sarcoidosis. A definitive diagnosis of TB requires a combination of clinical, radiographic, and microbiological findings. #Tuberculosis #Necrosis