Drug Metabolism - Pharmacokinetics | Pharmacology скачать в хорошем качестве

Drug Metabolism - Pharmacokinetics | Pharmacology

Watch next - Drug excretion & clearance:    • Drug Excretion & Drug Clearance | Pharmaco...   If you'd like to support EKG Science 💙 PayPal - https://www.paypal.com/paypalme/ekgsc... --- In this lecture EKG is going to cover drug metabolism. We're going to look at the processes involved in drug metabolism, including phase 1 and phase 2 reactions, as well as the key enzymes that catalyse these reactions. We're also going to break down the CYP450 system and explore what induces and inhibits these enzymes.  Table of Contents: 0:00 Intro 0:58 Definition, Purpose & Location 2:05 Overview: Lipophilic vs Hydrophilic Drug 3:25 Overview: Phase 1 & 2 5:40 Types of Metabolites 7:30 Phase 1 Reactions, CYP450 Enzymes & Genetic Polymorphism 11:45 Phase 2 Reactions 14:12 Factors Affecting Drug Metabolism 15:30 Enzyme Inducers 18:55 Enzyme Inhibitors For educational purposes only; NOT medical or other advice. Lecture Source: Ritter, J., Flower, R.J., Henderson, G., Yoon Kong Loke and Rang, H.P. (2018). Rang and Dale’s Pharmacology. 9th ed. Endinburgh: Elsevier. #pharmacokinetics #pharmacology #ekgscience