Endoscopic endonasal approach for sinonasal and anterior skull base malignancies скачать в хорошем качестве

Endoscopic endonasal approach for sinonasal and anterior skull base malignancies

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,[email protected], https://plus.google.com/communities/1... , ,https://plus.google.com/u/0/+Alexandr... ,    / @otolaryngologistorlent-med3259   ,    / @alexandrosg.sfakianakis4746   , https://twitter.com/g_orl?lang=el,   / alexandrossfakianakis  , Head Neck. 2018 Jan 17. doi: 10.1002/hed.25045. [Epub ahead of print] Endoscopic endonasal approach for sinonasal and anterior skull base malignancies in the elderly. Lepera D1, Leone F1, Volpi L1, Bignami M1, Karligkiotis A1, Lambertoni A1, Pistochini A1, Accorona R2, Nicolai P2, Castelnuovo P1. Author information 1 Department of Otorhinolaryngology, Ospedale di Circolo e Fondazione Macchi, University of Insubria, Varese, Italy. 2 Department of Otorhinolaryngology, Spedali Civili, University of Brescia, Brescia, Italy. Abstract BACKGROUND: The purpose of this study was to report the outcomes of endoscopic transnasal resection for sinonasal and anterior skull-base cancers in elderly patients. METHODS: A retrospective review was performed. The patients were divided into 2 groups, 70 years old and ≥70 years old and compared by univariate analysis. Prognostic factors were evaluated with a multivariate analysis. Survival rates were also calculated. RESULTS: Two hundred three elderly patients and 397 younger patients were enrolled in this study. The elderly patients reported lower survival rates than the younger patients. When melanoma and esthesioneuroblastoma were censored, the disease-specific survival (DSS) and recurrence-free survival (RFS) were similar. Complication rates were 17.5% without any statistical significance between the groups. Multivariate analysis revealed that histology, stage, surgical margins, and surgical approaches were independent predictors of survival in elderly patients. CONCLUSION: The endoscopic transnasal approach reported low mortality and morbidity rates also in geriatric patients, and age itself is not to be considered as a contraindication. © 2018 Wiley Periodicals, Inc. KEYWORDS: elderly; endoscopic; outcome; sinonasal cancer; skull base - video upload powered by https://www.TunesToTube.com