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APC (tumor suppressor) Gene Activation Frequency

APC, is a Tumor suppressor, preventing the uncontrolled growth of cancerous cells. 772.580 Hz APC (Adenomatous Polyposis Coli): APC is a tumor suppressor gene that plays a critical role in regulating cell growth and preventing the development of colorectal cancer. Mutations in the APC gene are associated with familial adenomatous polyposis (FAP), a hereditary condition characterized by the formation of numerous polyps in the colon and rectum. If left untreated, FAP often leads to the development of colorectal cancer. The APC protein is involved in the degradation of β-catenin, a key regulator of the Wnt signaling pathway. When the APC gene is mutated, β-catenin accumulates in cells, leading to uncontrolled cell division and the formation of polyps that can become cancerous over time. Early detection of APC gene mutations through genetic testing is crucial for individuals with a family history of FAP, as it allows for proactive surveillance and preventive measures such as regular colonoscopies and the potential for prophylactic surgery to reduce the risk of colorectal cancer. ⚠️ A gene may have more than one known or unknown function. ⚠️ A gene can activate or deactivate more than one other gene. ⚠️ Be sure to investigate the effects and characteristics of the relevant Gene.