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Development and Pilot Testing of a Simplified Version of the International Prostate Symptom Score Morgantini L1, Acar O1, Tirapegui F1, Ghafoor S2, Naha U2, Flores Martinez J1, Madurga Patuel B3, Kocjancic E1 1. University of Illinois at Chicago, Department of Urology, Chicago, U.S., 2. University of Illinois at Chicago, School of Medicine, Chicago, U.S., 3. Hospital Universitario Puerta del Mar, Cadiz, Spain KEYWORDS: Questionnaire, Benign Prostatic Hyperplasia (BPH), Quality of Life (QoL), Outcomes Research Methods, Male The International Prostate Symptom Score (IPSS) was created in 1992 and is the tool of choice for assessing the severity of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) and their impact on quality of life (QoL). The overall literacy in the U.S. has shown a steady decline over the last several decades (1). Males over 65 years of age, in whom LUTS-BPH is more prevalent compared to younger individuals, have the lowest literacy level. While 21% of the adults in the U.S. read below a 5th grade level, the conventional IPSS has a calculated readability at the 8th-grade level, corresponding to a 12-14 year old individual. Moreover, longitudinal studies demonstrated that the IPSS was not a reliable tool to assess temporal changes in LUTS-BPH (2), and many patients needed to be overseen by the healthcare provider to better understand and answer all the questions. We propose a simplified version of the IPSS (S-IPSS) which inherited the same goals as the original IPSS, but was tailored to the literacy level of the present-day elderly male population with LUTS-BPH in the U.S. In addition, given the growth of the Spanish-speaking population in the U.S., a Spanish version of the S-IPSS has also been developed. Our objective is to offer an updated, user-friendly tool for urologists and a more easily comprehensible questionnaire for patients. Read the full abstract text here: https://www.ics.org/2020/abstract/280