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Innovating for impact: Tackling chronic lung infections in cystic fibrosis through new antimicrobials REVIVE webinar in collaboration with CF AMR Syndicate. Speakers: Jane Davies, Professor of Paediatric Respirology and Experimental Medicine, National Heart and Lung Institute, Imperial College London (UK) Neill Gingles, Lead Scientist, Medicines Discovery Catapult (UK) David Richards, Chief Executive Officer, Clarametyx (USA) Moderator: Deborah O’Neil, Chief Executive Officer, NovaBiotics Ltd (UK) Chronic respiratory infections remain one of the most serious and persistent challenges in the care of people with cystic fibrosis (CF), even in the era of CFTR modulator therapy . This webinar brings together clinical experts, product developers, and innovators to explore the evolving infectious disease landscape in CF—focusing on the urgent need for novel antimicrobials, prioritizing difficult to treat Pseudomonas, Burkholderia, and NTM infections. It will highlight the unmet clinical needs, examine how well-designed target product profiles (TPPs) can guide meaningful innovation, and explore real-world challenges and opportunities in antimicrobial discovery and development for the CF community. 0:00 Webinar opening words 03:56 Presentation 1: The Clinical Picture of CF Infections: Why We Need New Antimicrobials (Jane Davies) 24:12 Presentation 2: Shaping Innovation Together: Designing and implementing Patient-Centric Target Product Profiles (TPPs) (Neill Gingles) 41:46 Presentation 3: Perspectives from Innovators: Navigating the CF Drug Discovery Landscape and the unique Challenges and opportunities in CF (David Richards) 58:18 Questions & Answers CF AMR Syndicate: https://cfamr.org.uk/ GARDP: https://www.gardp.org/ REVIVE: https://revive.gardp.org/ #webinar #GARDP #REVIVE #CFAMRSyndicate #antibiotics #antibioticresistance #cf #cystitcfibrosis #lungs #infection