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Epigenetic Aging Studies in Mammals

Presented By: Steve Horvath Speaker Biography: Dr Horvath's research lies at the intersection of aging research, epidemiology, chronic diseases, epigenetics, genetics, and systems biology. He works on all aspects of biomarker development with a particular focus on genomic biomarkers of aging. He developed a highly accurate multi-tissue biomarker of aging known as the epigenetic clock. Dr Horvath developed systems biologic approaches such as weighted gene co-expression network analysis which lend themselves for integrating gene genomic data sets. Webinar: Epigenetic Aging Studies in Mammals Webinar Abstract: In mammals, DNA methylation is an epigenetic mark that regulates gene expression by serving as a maintainable mark whose absence marks promoters and enhancers. Recent epidemiological studies demonstrate that DNA methylation levels are associated with aspects of biological aging in humans. We present universal mammalian epigenetic clocks that lend themselves for measuring age across mammalian species. We demonstrate that DNA methylation levels are strongly associated with maximum lifespan. These epigenetic clocks are expected to be useful for in vitro studies, animals models, and ultimately human clinical trials. Earn PACE Credits: 1. Make sure you’re a registered member of Labroots (https://www.labroots.com/ms/webinar/e...) 2. Watch the webinar on YouTube or on the Labroots Website (https://www.labroots.com/ms/webinar/e...) 3. Click Here to get your PACE credits: (https://www.labroots.com/credit/pace-...) Labroots on Social: Facebook:   / labrootsinc   Twitter:   / labroots   LinkedIn:   / labroots   Instagram:   / labrootsinc   Pinterest:   / labroots   SnapChat: labroots_inc