QTL mapping and GWAS (Bioinformatics S8E1) скачать в хорошем качестве

QTL mapping and GWAS (Bioinformatics S8E1)

Learn about phenotypes, heritability, homologous recombination, genetic linkage, and experimental (multi parental) crosses used in QTL analysis. This lecture is an introduction into Quantitative Trait Locus QTL mapping and genome-wide association analysis GWAS. This is a live-stream recording of the MSc and PhD lecture series: Bioinformatics for plant and animal sciences, given digitally during the Covid19 pandemic at the Humboldt University in Berlin organized and lectured by Dr Danny Arends. Lectures @ https://dannyarends.nl/bioinformatik/ Programming Assignments and Answers @ https://dannyarends.nl/bioinfo/ Playlist:    • Bioinformatics for Plant and Animal sciences   Chapters: 00:00 Welcome and Overview 00:40 A few words about phenotypes 01:24 Quantitative and qualitative phenotypes 03:35 Definition of heritability and environment 05:59 The broad-sense heritability of a phenotype 08:25 The narrow-sense heritability of a phenotype 10:11 Estimating heritability using a selection differential 14:01 Estimating heritability using analysis of variance (ANOVA) 15:50 DNA allows for random composition and mutation of heritable phenotypes 16:39 Homologous recombination of DNA happens during meiosis 1 24:20 Restriction fragment length polymorphism (RLPF) as genetic markers 28:48 Variable number of tandem repeats (VNTR) as genetic markers 30:55 Single nucleotide polymorphisms (SNPs) and SNP chips 32:36 Quantitative Trait Locus (QTL) mapping 34:05 Types of experimental crosses - The Backcross population 37:50 Drawing to visualize genetic inheritance of a backcross 48:25 Types of experimental crosses - The F2 population 50:32 Types of experimental crosses - Recombinant inbred lines (RILs) 53:59 Overview of different crosses used in QTL mapping 55:12 More complex (multi parental) crosses 56:38 Two flavors of linkage analysis (QTL and GWAS) Thanks for taking an interest in my channel 😄If you've made it this far down, support me by giving a like or subscribing. Join me during my live streams Thursday afternoons on Twitch @   / dannyarends   #bioinformatics #computationalbiology #lectureseries #programming #playlist #molecularbiology #englishstream #msc #phd #livestream #assignments #statisticsfordatascience #academia #academicyoutube #qtl #gwas #quantitativeanalysis #qualitativeanalysis #heritability #anova #homologous #snps #backcross #f2 #rils #linkage #linkageanalysis #experimentalcrosses #traits #complextrait #mendelian #vntrs #rlpf