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Tags: Cannabis Vape, Vaporizers, Adverse Events, Vape Ingredients, Vape Additives, Vitamin E Acetate, MCT Oil, Terpenes Shawna Vreeke presents "Toxicological Risk in Cannabis Vapes: Exogenous Additives and Their Implications for Consumer Safety" at CannMed 2025. We have developed a standard practice to perform toxicological risk assessments of exogenous ingredients used in cannabinoid formulations for vaporization devices to reject or accept with calculated acceptable use limits based on the available scientific literature and new approach methodologies. Using this practice, this study aims to evaluate the potential risks these additives pose to users and identify harmful compounds that are currently present in vaporizer products on the market. Through quantitative GC/MS analysis of a targeted list of compounds in products from multiple terpene manufacturers, this study detected various toxic additives that could compromise consumer health. This session will review the safety assessment framework adopted as a global standard by ASTM. It will highlight specific higher-risk ingredients and identify how prevalent they are in vaporization products currently in the cannabis market. The findings highlight an urgent need for a toxicological review of non-cannabinoid additives used in inhalable products to reduce potential health risks. By implementing rigorous safety standards, the cannabis industry can reduce the risk to consumer health, prevent over-regulation and flavor bans, and support the longevity of the industry. Learning Objectives: ⦾ Learn about the ASTM newly adopted risk assessment standard for cannabis vaporizer additives ⦾ Gain insights into specific compounds found in vape additives that pose potential toxicological risks 0:00 - Introduction to Toxicology in Cannabis 0:36 - Understanding Risk: Hazard and Exposure 4:24 - Inhalation vs. Oral Consumption 5:10 - Exogenous Ingredients in Cannabis Vapes 6:27 - The Need for Toxicology in Vaping 9:16 - Would Toxicology Have Prevented the Vaping Crisis? 12:22 - The Dangers of MCT Oil in Vapes 14:14 - True Terpenes' Toxicological Program 15:25 - Competitor Blend Analysis and Findings 17:15 - Problematic Vaping Compounds: Benzaldehyde 18:24 - The Dangers of Maltol and Ethyl Maltol 20:01 - Why Cinnamaldehyde is a Problem 22:10 - Call to Action: Research on Nitrosamine Compounds 23:14 - Tools for Performing Toxicological Risk Assessments 24:42 - Next Steps for a Safer Cannabis Industry 26:44 - Q&A: In-Depth Discussion with the Audience Learn More about CannMed: https://cannmedevents.com/ Sign Up for Our Newsletter: https://share.hsforms.com/1oi57oJDnRN... The CannMed 25 Innovation & Investment Summit showcased its first international venue, the Wyndham Grand Rio Mar Golf & Beach Resort in Puerto Rico from June 17 - 20, 2025. Since its inception at Harvard Medical School in 2016, CannMed has earned a reputation as the premier destination for cutting-edge research, emerging technologies, and investment opportunities. CannMed 25 continues this tradition with medicinal plant researchers, clinicians and venture capitalists who view this Summit as the industry’s number one showcase for the latest advances in plant-based science, medicine, cultivation, and safety.