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Dr Boris E. Malyugin is an internationally recognized Ophthalmologist, Professor of Ophthalmology and Deputy Director General at the S. Fyodorov Eye Microsurgery State Institution. He also served as the President of the Russian Ophthalmology Society, European Society of Cataract and Refractive Surgeons Board and member of several other societies. He has received the C. Binkhorst Award by the American Society of Cataract and Refractive Surgery (ASCRS) and also has` several publications and books on his credits. The eye lens composed of epithelial and superficial fiber cells and is connected with retina through the vitreous and vitreous membrane. The entire anatomy supports the structure and function of the eye. However, vitreous detachment is a clinical condition where vitreous separates from the retina. This condition is common among the geriatric population. In this exclusive commentary, Dr Boris E. Malyugin shares his insights on the Inter-Relationship Between The Lens And The Vitreous.