Nasal Decongestant | Introduction & Mechanism of Action | Nasal Decongestant | Alfa receptor Agonist скачать в хорошем качестве

Nasal Decongestant | Introduction & Mechanism of Action | Nasal Decongestant | Alfa receptor Agonist

Download "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Test and other GPAT Materials - https://play.google.com/store/apps/de... A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness). Intranasal corticosteroids can also be used as decongestants and antihistamines can be used to alleviate runny nose, nasal itch, and sneezing. Topical decongestants on the topical application as a dilute solution (0.05–0.1%) produce local vasoconstriction. Regular use of decongestants for long periods should be avoided because mucosal ciliary function is impaired: atrophic rhinitis and anosmia (loss of the sense of smell) can occur due to persistent vasoconstriction. The vast majority of decongestants act via enhancing norepinephrine (noradrenaline) and epinephrine (adrenaline) or adrenergic activity by stimulating the α1-adrenergic receptor since they mediate vasoconstriction and constricting nasal vasculature causes decongestion of the nasal mucosa. This induces vasoconstriction of the blood vessels in the nose, throat, and paranasal sinuses, which results in reduced inflammation (swelling) and mucus formation in these areas. Decongestant nasal sprays and eye drops often contain oxymetazoline and are used for topical decongestion. Pseudoephedrine acts indirectly on the adrenergic receptor system, whereas phenylephrine and oxymetazoline are direct agonists. Get in touch with the solution by just clicking following links- Facebook Group-   / solutionpharamcy   Facebook Page-   / pharmavideo   New channel (Pharmacy Dictionary) -    / @pharmacydictionary   Instagram-   / solutionpharmacy   E-Mail for official and other work - [email protected] LinkedIn-   / pushpendrakpatel   #solutionpharmacy #Pharmacologyclass #GPATonlinetest