Cryopreservation technologies: Pioneers of cell therapy #4 скачать в хорошем качестве

Cryopreservation technologies: Pioneers of cell therapy #4

Cryopreservation is revolutionizing cell therapy, thanks in part to John Morris. Since he first froze T cells at Cambridge University in the 1970s, John Morris’s name has become synonymous with cryopreservation and its various associated processes. His pivotal research was published in the Nature scientific journal and, since then, Morris has remained at the forefront of cryogenic science. When CAR T became a reality for patients many years later, the limitations of cold chain logistics hindered progres. Morris and his team of engineers poured passion and an innovative spirit into developing disruptive liquid nitrogen-free cryopreservation technologies, such as the VIA Freeze™ range of controlled-rate freezers from Cytiva, to build the best possible process for patients. In this episode, these "rock star scientists" discuss the impact of cryopreservation on the development of CAR T therapies, how a surprising discovery in cell thawing led to VIA Thaw™ dry automated thawer systems for cell therapy delivery, and why the cryogenic cold chain is a key enabler of globalizing personalized medicine. For more stories from Cytiva, visit: https://www.cytivalifesciences.com/en... For more information on cell therapy cryo-logistics, visit: https://www.cytivalifesciences.com/en... Episode features: John Morris, Aaron Dulgar-Tulloch, Stephen Lamb and Chris Creasey. Chapters: 00:00 Intro 00:26 Understanding cryogenic freezing and cryopreservation 01:29 Experts in cold chain engineering 02:07 Identifying cryo-logistics as a key step for CAR T 03:21 The challenges of liquid nitrogen shipping 04:09 Creating electric-powered, controlled-rate freezing 05:34 A surprising discovery in cell thawing 06:14 VIA Thaw™ system: Designed by end-users 07:06 Helping to globalize CAR T treatments 07:59 How it feels to deliver medical miracles 08:36 End #cryogenics #lifesciences #biopharma #celltherapy