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References: Chabanas M., Luboz V. & Payan Y. (2003). Patient specific Finite Element model of the face soft tissue for computer-assisted maxillofacial surgery, Medical Image Analysis, Vol. 7, Issue 2, pp. 131-151. Bucki M., Lobos C. & Payan Y. (2010). A Fast and Robust Patient Specific Finite Element Mesh Registration Technique: Application to 60 Clinical Cases. Medical Image Analysis, Vol. 14, pp. 303--317. This work addresses the prediction of face soft tissue deformations resulting from bone repositioning in maxillofacial surgery. A generic 3D Finite Element model of the face soft tissues was developed. Face muscles are defined in the mesh as embedded structures, with different mechanical properties (transverse isotropy, stiffness depending on muscle contraction). Simulations of face deformations under muscle actions can thus be performed. In the context of maxillofacial surgery, this generic soft-tissue model is automatically conformed to patient morphology by elastic registration, using skin and skull surfaces segmented from a CT scan. Some elements of the patient mesh could be geometrically distorted during the registration, which disables Finite Element analysis. Irregular elements are thus detected and automatically regularized. This semi-automatic patient model generation is robust, fast and easy to use. Therefore it seems compatible with clinical use.