what does U=U mean? // hiv undetectable=untransmittable (science-based) скачать в хорошем качестве

what does U=U mean? // hiv undetectable=untransmittable (science-based)

What does HIV U=U mean? What does HIV undetectable mean? Find out here! Q: Can I spread HIV to my negative partner if I am undetectable? A: No Given the scientific evidence, HIV positive people with a suppressed viral load (less than 200 copies/ml) can not transmit the virus sexually. With or without a condom. Oral, vaginal, anal sex. Whether the partner takes PrEP or not. Undetectable = Untransmittable. This holds true ONLY if U is U (undetectable is undetectable)! Q: Should I still wear a condom? A: Yes / No HIV can’t be spread (if U is U), BUT not wearing a condom puts you at risk for other STIs and possible pregnancies. It’s up to the couple if they want to use one. ►►► TIMELINE 0:00 Intro 1:02 What is HIV undetectable? 3:33 What is U=U? 7:53 Implications of U=U 9:52 Food for thought 10:33 Outro ►►► ABBREVIATIONS U=U = Undetectable=Untransmittable HIV = Human Immunodeficiency Virus VL = viral load ART = antiretroviral treatment PrEP = Pre-exposure prophylaxis PEP = Post-exposure prophylaxis CDC = Centers for Disease Control and Prevention NIH = National Institutes of Health ►►► SOURCES It’s a LOT, I know, but I wanted to be as transparent as possible :) (1) Selik&Linley 2018 Viral Loads Within 6 Weeks After Diagnosis of HIV Infection in Early and Later Stages: Observational Study Using National Surveillance Data (2) When is someone most infectious? Wawer+2005 Rates of HIV-1 Transmission per Coital Act, by Stage of HIV-1 Infection, in Rakai, Uganda Hollingsworth, Anderson, Fraser 2008 HIV-1 Transmission, by Stage of Infection (3) Do recently infected people spread HIV more than those who already know they have it? (First source is a bit outdated, btw) Marks+2006 Estimating sexual transmission of HIV from persons aware and unaware that they are infected with the virus in the USA Moore+2009 Number of Named Partners and Number of Partners Newly Diagnosed With HIV Infection Identified by Persons With Acute Versus Established HIV Infection (4) Credit for plot: NIAID shorturl.at/qstxC Vernazza+2000 Potent antiretroviral treatment of HIV-infection results in suppression of the seminal shedding of HIV Graham+2007 Initiation of antiretroviral therapy leads to a rapid decline in cervical and vaginal HIV-1 shedding (5) A Comparison of Two Ways to Manage Anti-HIV Treatment (The SMART Study) (2006) (6) U=U posters POZ: https://www.poz.com/ Terrence Higgins Trust: https://www.tht.org.uk/our-work/our-c... Russia: https://life4me.plus/campaigns/nravno... Switzerland: https://aids.ch/de/was-wir-tun/aktivi... Planned Parenthood: shorturl.at/hpquE Italy: https://www.lila.it/it/campagne/968-c... I can’t transmit HIV to anyone: https://www.untransmittable.org/ No soy un riesgo : http://iamnotarisk.org/index.html (7) PARTNER 1 study Rodger+2016 Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-Positive Partner Is Using Suppressive Antiretroviral Therapy (8) Anal sex poses a higher transmission rate Patel+2014 Estimating per-act HIV transmission risk: a systematic review (9) PARTNER study (PARTNER 1+2 but geared towards the second part) (2019) Rodger+2019 Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study (10) Opposites Attract Bavinton+2018 Viral suppression and HIV transmission in serodiscordant male couples: an international, prospective, observational, cohort study (11) Swiss Statement (2008) «Swiss Statement»: bilan deux ans après (sorry it’s only in French) (12) Compilation of other studies. There are plenty more out there than what’s just listed ;) HPTN 052 - Cohen+2011 Prevention of HIV-1 Infection with Early Antiretroviral Therapy Rakai Project Study Group - Quinn+2000 Viral Load and Heterosexual Transmission of Human Immunodeficiency Virus Type 1 Spain-based Study - Jesus+2005 Effectiveness of Highly Active Antiretroviral Therapy in Reducing Heterosexual Transmission of HIV Thailand-based Study - Tovanabutra+2001 Male Viral Load and Heterosexual Transmission of HIV-1 Subtype E in Northern Thailand Africa-based Study - Donnell+2010 Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis (13) U=U widely accepted by 997 organizations in 102 countries as of 17 August 2020 https://www.preventionaccess.org/cons... (14) Aims of the U=U campaign Check out Prevention Access: https://www.preventionaccess.org/about (15) Kalichman+2015 Sexual Behaviors and Transmission Risks among People Living with HIV: Beliefs, Perceptions, and Challenges to Using Treatments as Prevention ►►► OTHER HELPFUL LINKS PARTNER Q&A: https://i-base.info/qa-on-the-partner... U=U in different languages: https://i-base.info/category/resource... ►►► THANKS FOR WATCHING :)