What is DXM? Science, Effects, & Risks | What is Robotripping? скачать в хорошем качестве

What is DXM? Science, Effects, & Risks | What is Robotripping?

What is DXM, and why is an over the counter cough medicine able to induce a powerful dissociative and psychedelic experience? In this deep dive, we explore the full story of dextromethorphan (DXM): how it works in the brain, why it’s considered both a dissociative and psychedelic, and the surprising science behind its potential as an antidepressant and neuroprotective agent. 🛒 Pre-Trip Packets (USA only): Support stomach comfort, Calm the mind, Promote a peaceful trip (DISCOUNT CODE: temporary15) https://triptimeessentials.com/produc... DanceSafe Testing Kits: https://dancesafe.org/r/triptimeessen... We’ll break down the mechanisms of action (NMDA antagonism similar to Ketamine, sigma 1 receptor activity, serotonin effects), promising studies on depression and stroke recovery, the phenomenon of robotripping, expected effects at different doses, risks, interactions, side effects, and the most important harm reduction practices. We even discuss Auvelity, the combination medicine of DXM and Wellbutrin. Whether you’re here for science, safety, or curiosity, this video covers the full picture of DXM. Aaron's Facilitating Business: https://goldenfacilitator.com/ References and Resources: DXM PubMed Overview: https://www.ncbi.nlm.nih.gov/books/NB... DXM For Depression Systematic Review: https://pubmed.ncbi.nlm.nih.gov/33682... DXM plus Wellbutrin for depression: https://pubmed.ncbi.nlm.nih.gov/37859... High Dose DXM vs Psilocybin Study: https://pubmed.ncbi.nlm.nih.gov/38152... Josie Kins’ DXM Effect Index (basically DXM plateaus): https://www.effectindex.com/articles/dxm CYP2D6 Inhibitor Medications: https://pmc.ncbi.nlm.nih.gov/articles... CBD as a CYP2D6 inhibitor- https://pubmed.ncbi.nlm.nih.gov/21821... CBD impacts drug metabolism: https://www.sciencedirect.com/science... Different Phytocannabinoid’s Effect on CYP2D6 (THCV, Beta-Caryophyllene): https://pmc.ncbi.nlm.nih.gov/articles... DXM toxicity: https://www.ncbi.nlm.nih.gov/books/NB... DXM triggers false positive for PCP https://academic.oup.com/labmed/artic... Alzheimer’s medication targeting sigma 1 receptors (AF710B): https://pubmed.ncbi.nlm.nih.gov/29291... Psilocin Acts as a SERT blocker: https://pmc.ncbi.nlm.nih.gov/articles... DXM stroke recovery: https://www.ahajournals.org/doi/epdf/... DXM Neuropathic Pain: https://www.sciencedirect.com/science... DXM Postoperative Pain: https://www.sciencedirect.com/science... -DXM autism: https://pubmed.ncbi.nlm.nih.gov/17175... -DXM autism newer study: https://pubmed.ncbi.nlm.nih.gov/30109... -Free DNA Upload Analysis, can assess CYP2D6 status: https://genvue.geneticgenie.org/ Trip Time Essentials delivers scientifically accurate information, safety advice, and other tools and useful information regarding the use of psychedelics. We explore dose ranges, duration, effects, visuals to expect, mechanism of action & pharmacology, as well as supplements like the Pre-Trip product that can help alleviate common side effects. We never recommend the use of illegal substances. All content is for educational and entertainment purposes, and does not substitute for medical advice. Chapters: 00:00 Intro 00:42 History & Background of DXM 02:05 DXM Research Highlights 03:25 Mechanism of Action of DXM and DXO 09:14 DXM Effects on Brain Activity 11:06 High Dose DXM vs Psilocybin Research Part 1 12:04 DXM For Depression 13:13 DXM for Stroke, TBI, Pain, Autism 15:10 DXM vs Psilocybin Part 2 16:35 Expected Effects of DXM 19:28 Dosage & Intensity (Levels/Plateaus) 22:27 Drug Interactions with DXM 26:20 Genetic Difference in Metabolism 27:46 Risks & Side Effects 30:29 DXM Duration & Half-Life Outtro Music Credits: Song: Last Summer Composer: Ikson Website: / ikson License: Free To Use YouTube license youtube-free #dxm #psychedelicscience #psychedelicresearch