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Direct Calorimetry - Numericals of Thermochemistry by Tariq Pathan DIRECT CALORIMETRY: Direct calorimetry obtains a direct measurement of the amount of heat generated by the body within a structure large enough to permit moderate amounts of activity. These structures are called whole-room calorimeters. Direct calorimetry provides a measure of energy expended in the form of heat. The technique of direct calorimetry has several disadvantages. The structure is costly, requires complex engineering, and appropriate facilities are scarce around the world. Subjects must remain in a physically confined environment for long periods. In addition, direct calorimetry does not provide any information about the nature of substrates that are being oxidized to generate energy within the body.