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What Are Cannabinoids

What Are Cannabinoids? Professor DeBacco Phytocannabinoids Explained Phytocannabinoids are a secondary metabolite produced by many plants and liverworts, however they are produced in the greatest concentrations and variations in C. sativa (Gulck 2020). Phytocannabinoids are bioactive terpenoids that were thought to be exclusive to Cannabis sativa, but have now also been discovered in Rhododendron species, some legumes, the liverwort genus Radula, and some fungi. Cannabinoids or Phytocannabinoids? Phytocannabinoids are any cannabinoid produced in the trichomes of a cannabis plant. Phytocannabinoids are fatty acids synthesized in the trichomes of C. sativa, and also in the trichomes of multiple other species. Phytocannabinoids interact with our body's receptors to produce numerous psychotropic and therapeutic effects. Cannabinoids are a class of lipophilic molecules that interact with the body's endocannabinoid system (ECS). Often are used as interchangeable terms. Endocannabinoids are what is produced in animals. Properties The phytocannabinoids are mostly insoluble in water but are soluble in alcohol and fat and other non-polar organic solvents. In alkaline conditions, they can form water-soluble phenolate salts, being essentially phenols. Overview of Cannabinoids Overview of Cannabinoids Derived from an Orcinoid, Varinoid, Olivetoid, or Bibenzyl/Aralkyl Backbone Black structures have been isolated from natural sources Blue structures have not yet been found in planta. “Side Chain” (SC) Cannabinoids The general side-chain cannabinoids in C. sativa can be divided into ten general groups Why Are Cannabinoids Produced? Plants produce cannabinoids as a form of defense against insect feeding and/or stressful environmental conditions such as UV light and desiccation The human body produces cannabinoids for survival through the activation of homeostasis. Cannabinoids and Humans They are “bioactive” in human beings in the sense that they bind to the endogenous cannabinoid system or ECS, which results in a plethora of physiological responses. The effect of these drugs can treat many different diseases ranging from inflammation to anxiety. Link to Lecture Slides: https://drive.google.com/file/d/1Eg_-... *Due to the description character limit the full work cited for "What Are Cannabinoids" can be viewed at... https://drive.google.com/file/d/1F4GT...