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sqadia.com gives you a very interesting video on the topic of Phagocytic cells and the Reticuloendothelial system (RES). Here you will learn about the Reticuloendothelial system and all phagocytes, together with those cells that are mainly not involved in phagocytosis but occasionally can phagocytose foreign particles. ▬ Phagocytosis ▬▬▬▬▬▬▬▬▬▬ Phagocytosis is a normal cellular process for ingesting and eliminating particles larger than 0.5 micrometers in diameter, which can be cells' own debris or waste, microorganisms, foreign substances, and apoptotic cells. Cells that undergo a process of phagocytosis are called Phagocytes or Phagocytic cells of the Immune system. ▬ Reticuloendothelial System (RES) ▬▬▬▬▬▬▬▬▬▬ The body-wide system of phagocytic cells that mainly phagocytize foreign particles, is known as the Reticuloendothelial system (RES). The reticuloendothelial system (RES) is a heterogeneous population of phagocytic cells that play an important role in the clearance of particles and soluble substances in the circulation and tissues, and forms part of the immune system. Cells that are mainly involved in this system are: 🔹Endothelial cells 🔹Reticular cells 🔹Various types of Macrophages 👉 Endothelial cells Endothelial cells: make the inner lining of blood vessels and are able to take up endogenous or exogenous debris etc., but these are not truly phagocytic, but provide structural support to blood vessels. 👉 Reticular cells The main supporting or ‘stromal’ cell of lymphoid organs, is usually associated with the collagen-like reticulin fibers and is not easily distinguished from fibroblasts or from other branching or ‘dendritic’ cells. 👉 Monocytes and Macrophages Monocytes are myeloid cells which means they have bone marrow origin. Monocytes in the blood are immature cells migrating to their site of activity. Monocytes migrate into tissues where they mature into macrophages and take on a number of specialized forms. All macrophage forms have long life spans and survive in the tissue for months or years. The major phagocytic cells involved in the Reticuloendothelial system are macrophages. So, this system is also named a ´Mononuclear phagocytic system´ (MPS). Inside tissues, macrophages take on a number of specialized forms, Like: 🔵 Giant and Epithelioid Cells 🔵 Osteoclasts 🔵 Microglia 🔵 Kupffer cells 🔵 Dendritic cells So that was all about Phagocytic cells and the Reticuloendothelial system!