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How do imaging, intravascular lithotripsy, and equipment selection come together to effectively target coronary calcium? In this episode of BackTable, interventional cardiologists Dr. Robert Riley (Overlake Medical Center in Bellevue, Washington) and Dr. Yousif Ahmad (UCSF) trade techniques and discuss various aspects of calcium modification in complex percutaneous coronary intervention (PCI). --- This podcast is supported by: Shockwave Medical https://shockwavemedical.com/ --- SYNPOSIS The discussion begins with an overview of intravascular lithotripsy (IVL), including its mechanism of action, ideal lesion characteristics, and performance across varying calcium morphologies. The conversation then expands to comparative decision-making among atherectomy, specialty balloons, and IVL, emphasizing how intravascular imaging informs procedural planning and real-time optimization. Key clinical data are reviewed, including the Disrupt CAD I-IV series as well as findings from the Short-Cut and VICTORY trials. The episode concludes with a forward-looking discussion on emerging technologies and the ongoing challenge of treating calcified nodules, one of the most demanding substrates in coronary intervention. --- TIMESTAMPS 00:00 - Introduction 04:16 - Complex PCI and Calcium Modification Tools 04:43 - Intravascular Lithotripsy (IVL) Insights and Evolution 12:08 - Calcium Modification Algorithms and Techniques 27:24 - IVUS vs. OCT Imaging and Specialty Balloons 32:12 - Challenges in Implementing New Techniques 37:09 - Influential Studies in Calcium Modification 40:52 - Recent Studies: Short-Cut and VICTORY 53:11 - Future of Calcium Modification Technologies 57:48 - Final Thoughts --- RESOURCES Dr. Robert Riley https://www.scai.org/robert-f-riley-m... Dr. Yousif Ahmad https://profiles.ucsf.edu/yousif.ahmad Intravascular imaging-guided coronary drug-eluting stent implantation: an updated network meta-analysis https://pubmed.ncbi.nlm.nih.gov/38401... Coronary intravascular lithotripsy for severe coronary artery calcification: The Disrupt CAD I-IV trials https://www.sciencedirect.com/science... Orbital Atherectomy vs. Conventional Balloon Angioplasty in Severely Calcified Coronary Arteries Prior to DES Implantation - ECLIPSE https://www.acc.org/Latest-in-Cardiol... Shockwave Lithoplasty Compared to Cutting Balloon Treatment in Calcified Coronary Disease - A Randomized Controlled Trial (Short-Cut) https://clinicaltrials.gov/study/NCT0... The Value of IVL Compared To OPN Non-Compliant Balloons for Treatment of RefractorY Coronary Lesions (VICTORY) Trial (VICTORY) https://clinicaltrials.gov/study/NCT0... --- BackTable Cardiology is a podcast for clinical and interventional cardiologists, cardiac surgeons, and other healthcare professionals involved in cardiovascular care. This show brings together expert voices from across the field to explore the latest in cardiology—from evolving guidelines and innovative devices to real-world case discussions and multidisciplinary collaboration. Get notified when new episodes drop! Subscribe to the BackTable Cardiology Podcast on your go-to podcast platform, and follow us on your social media platform of choice for regular updates. ► https://www.backtable.com/shows/cardi... #CV25 #cardiology #coronaryarterydisease #interventionalcardiology