Turner syndrome (gonadal dysgenesis) - Usmle step 1 lecture скачать в хорошем качестве

Turner syndrome (gonadal dysgenesis) - Usmle step 1 lecture

📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:-   / drgbhanuprakash   📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr 📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash Turner syndrome (gonadal dysgenesis) is a result of partial or total loss of one X chromosome secondary to nondisjunction during gametogenesis of parents or a post-fertilization mitotic error. Although 95% abort spontaneously in the first trimester, there are still a significant number of females that are affected. Lymphedema is prominent in utero and leads to many of the characteristic cutaneous manifestations at birth. Newborns are small for gestational age and have redundant neck skin as well as prominent edema of the hands and feet. Approximately one third of patients are diagnosed at birth because of the edema. The puffiness of the hands and feet gradually resolve. The nails tend to be hypoplastic, deep-set, and the fingernails can be hyperconvex. Patients with Turner syndrome can have associated coarctation of the aorta and kidney abnormalities. With proper treatment of the congenital anomalies, patients have a normal life span.