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Watch the Full Video at https://www.jove.com/v/52112/a-novel-.... A Novel In vitro Model for Studying the Interactions Between Human Whole Blood and Endothelium - a 2 minute Preview of the Experimental Protocol Sofia Nordling, Bo Nilsson, Peetra U. Magnusson Uppsala University, Department of Immunology, Genetics and Pathology; The accessibility of reliable models to investigate vascular blood interactions in humans is lacking. We present an in vitro model of cultured primary human endothelial cells combined with human whole blood to investigate cellular interactions both in the blood (ELISA) and the vascular compartment (microscopy). Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments