Regulation of tetraspanin CD63 in CML progression: single-cell analysis of asymmetric HSC division скачать в хорошем качестве

Regulation of tetraspanin CD63 in CML progression: single-cell analysis of asymmetric HSC division

Ali Turhan, MD, PhD, University of Paris-Saclay, Paris, France, discusses the findings of a single-cell analysis of genes involved in asymmetric hematopoietic stem cell (HSC) division in chronic myeloid leukemia (CML). During the chronic phase of CML, the tetraspanin CD63 was overexpressed on HSCs. However, during blast crisis in the progression of the disease to acute myeloid leukemia (AML), there was decreased expression of this gene. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.