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Watch the Full Video at https://www.jove.com/v/50933/quantita.... Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus - a 2 minute Preview of the Experimental Protocol Daniel E. Venegas-Pino, Nicole Banko, Mohammed I. Khan, Yuanyuan Shi, Geoff H. Werstuck McMaster University, Department of Biochemistry and Biomedical Sciences; McMaster University, Thrombosis and Atherosclerosis Research Institute; We describe procedures to quantify and characterize atherosclerotic lesions in mouse models using precision sectioning of the aortic sinus and ascending aorta combined with histochemical and immunohistochemical analysis. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments