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Minutes matter when it comes to fluorouracil poisoning. Immediately contact your veterinarian or local emergency veterinary hospital if your pet licks the area where you applied fluorouracil or chews the container and consumes some of the fluorouracil. Make sure the veterinarian knows your pet was exposed to fluorouracil. Fluorouracil, also called “5-FU” or “5-fluorouracil,” is an FDA-approved chemotherapy drug commonly used to treat a wide variety of cancers in people, including some types of skin cancers and a condition called solar or actinic keratosis, which can lead to skin cancer. It’s also used to treat warts in children and occasionally in veterinary medicine to treat cancers in horses. Fluorouracil is available either as a solution for injection or as a topical cream or topical solution that’s applied on the skin. Pets can be exposed to fluorouracil by chewing on containers, usually tubes, of topical fluorouracil or by licking the area of your skin where you applied the medicine. FDA has not yet received any reports of fluorouracil poisoning in cats or other pets but recommends that this drug also be kept away from all pets for their safety.