Bioavailability VS. Bioactivity скачать в хорошем качестве

Bioavailability VS. Bioactivity

A whole science exists which quantifies the different ways in which drugs interact with our bodies. Pharmacokinetics (PK) quantifies where we can find a drug from the moment it’s ingested, to the moment it is gone. Summarized by the neat acronym ADME (Absorption, Distribution, Metabolism, and Excretion), PK tells us how much of the compound reaches the target tissue. In the case of cannabinoids, this may be the central nervous system, the GI tract, nerve endings, or cutaneous vasculature. These parameters are separate from Bioactivity, determined by the branch called Pharmacodynamics, which tells us how much a targeted receptor or signaling system is influenced in the presence of the drug that’s there. Table of contents 00:00:20 Introduction 00:04:10 Correlation between water-solubility and bioactivity 00:06:30 Studying CBD safety 00:11:18 Water-soluble CBD and nanoparticles 00:13:44 Brain scanning 00:16:35 Bioavailability vs bioactivity 00:21:26 Bioavailability and bioactivity for entrepreneurs 00:31:08 Q&A