メラトニンは、脳の松果体から分泌される重要なホルモンであり、主に睡眠と覚醒のリズムを調整する役割を担っています。 скачать в хорошем качестве

メラトニンは、脳の松果体から分泌される重要なホルモンであり、主に睡眠と覚醒のリズムを調整する役割を担っています。

#睡眠のための音楽 #睡眠不足 #瞑想ガイド #5分で寝れる #リラックス音楽 #ストレスケア #ストレス #music #sleepmusic30minutes Melatonin is synthesized through the following four enzymatic reactions using the essential amino acid tryptophan as a precursor. Tryptophan hydroxylase (TPH): Converts tryptophan to 5-hydroxytryptophan (5-HTP). Aromatic L-amino acid decarboxylase (AADC): Converts 5-HTP to serotonin (5-HT). Serotonin is a neurotransmitter that is also involved in regulating mood and emotions. N-acetyltransferase (AANAT): Converts serotonin to N-acetylserotonin. The activity of this enzyme is the rate-limiting step in melatonin synthesis and is activated by darkness. Hydroxyindole-O-methyltransferase (HIOMT): Converts N-acetylserotonin to melatonin. Melatonin synthesis is mainly active at night, especially in the dark. Light stimuli are transmitted via the retina to the suprachiasmatic nucleus (the center of the body's internal clock), and the signal is then transmitted to the pineal gland, suppressing melatonin synthesis.