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Subscribe to our channel: / @optispan Related episodes: People are GETTING THIS WRONG about Supplements & My Supplement List: • People are GETTING THIS WRONG about S... Are DEXA scans ACCURATE? What YOU NEED to KNOW: • Are DEXA scans ACCURATE? What YOU NEE... The Importance of Body Composition & Ways YOU can measure it: • The Importance of Body Composition & ... If you're listening to this podcast, you've probably caught wind of at least some of the many things you can do to improve and take control of your health and wellbeing. For every legitimate healthspan intervention supported by rigorous research that's out there, there exist a bunch of dubious longevity solutions that have no real scientific backing behind them. The challenge lies not just in identifying what works, but also in resisting the allure of snake oil solutions that promise effortless transformations. Which interventions are actually crucial for optimizing your healthspan, which are just "nice-to-have", and which are downright pointless? In this episode, Matt and Nick go through over twenty popular strategies for healthspan optimization and grade their usefulness from A to F. 0:00 Trailer 0:49 Introduction 2:07 Regular dental visits/oral care 3:31 DEXA scans 4:43 Bioimpedance scale 5:16 Fitness wearable 5:45 Bloodwork 5:59 Multi-cancer early detection testing 7:07 Epigenetic age testing 8:03 Nicotinamide mononucleotide (NMN) 9:56 Resveratrol 11:19 Rapamycin 12:55 Vitamin D3 14:53 Genetic testing, e.g. 23andMe 16:20 Sleep 16:46 Intermittent fasting/time-restricted eating 24:42 Exercise (cardio + resistance training) 26:52 Cross-training 28:00 Creatine monohydrate 28:48 Not smoking 30:33 Not drinking 33:12 Continuous glucose monitors 33:40 Microbiome analysis 38:15 Hormone replacement therapy 45:34 Skin aging clock 46:24 Cognitive function tests 50:58 Wrapping up Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twitter: / optispanpodcast Twitter: / optispan Twitter: / mkaeberlein Linkedin: / optispan https://www.optispan.life/ Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it. On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!