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Welcome back to Dental Digest with The Study Boards! In Episode 15, we’re diving into one of the most intriguing and board-relevant developmental cysts — the Glandular Odontogenic Cyst (GOC). Rare, locally aggressive, and often mistaken for a mucoepidermoid carcinoma, GOC is a favorite for INBDE, AFK, and ADAT exam questions. In this episode, you’ll quickly master: ✅ What exactly is a GOC? Its developmental origin and why it’s considered an odontogenic cyst with glandular differentiation. ✅ Clinical Presentation: Slow-growing, painless jaw swelling—most often in the anterior mandible of adults. ✅ Radiographic Appearance: Well-defined, unilocular or multilocular radiolucency, often with cortical expansion. ✅ Histopathologic Hallmarks: Non-keratinized epithelial lining with hobnail (cuboidal) cells Mucous/goblet cells and microcystic spaces Eosinophilic “plaques” within the lining Pseudoglandular pattern mimicking salivary glands ✅ Differential Diagnosis: Lateral periodontal cyst Botryoid odontogenic cyst Mucoepidermoid carcinoma (key mimic!) ✅ Management: Enucleation with close follow-up due to high recurrence potential. ✅ Exam Tip: When you see “cystic lesion with gland-like structures in the anterior mandible,” think GOC before mucoepidermoid carcinoma! 🎯 Why This Matters for Your Boards: GOC tests your ability to distinguish developmental odontogenic cysts from salivary gland neoplasms—a favorite trick question on INBDE and AFK. 🧠 Perfect For: INBDE • AFK • ADAT • NDEB • Oral Pathology Review 📲 Follow The Study Boards: 🔹 Facebook: facebook.com/thestudyboards 🔹 Instagram: instagram.com/thestudyboards