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This video shows multiple Hepatic metastases. Liver metastases mean that cancer in one part of the body has spread to a person's liver. In these cases, the person has advanced, or stage 4, cancer. The prognosis for liver metastases tends to be poor, with a roughly 11% survival rate for 5 years. Liver metastases are cancerous tumors that have spread (metastasized) to the liver from another part of the body. These tumors can appear shortly after the original tumor develops, or even months or years later. This information is about cancer that has spread to the liver. The prognosis for liver metastases tends to be poor, with a roughly 11% survival rate for 5 years. Treatments can help reduce the symptoms and shrink the tumor, but typically, there is no cure for liver metastases. Symptoms of Liver Metastases (Secondary Liver Cancer) • an overall feeling of weakness and poor health. • loss of appetite. • weight loss. • fever. • fatigue. • bloating. • itching. • swelling of the legs (edema). Clinical presentation of Hepatic metastasis. Liver metastases are usually asymptomatic and found during investigations of a malignancy that has presented in other ways. If the hepatic metastatic burden is large then the presentation or symptoms related to the liver disease may include: Localized pain and tenderness due to capsular stretching Disordered liver metabolic function Ascites Low-grade fever One of the main difficulties in hepatic imaging for metastatic disease is the high prevalence of benign liver lesions that can be misinterpreted as evidence of metastatic disease, thus dramatically changing a patient's stage, and therefore treatment options. Hepatic metastases are the tumors that had spread to the liver from other areas of the body. As cancer cells mostly have aggressive tendencies and so they are going to invade other areas of the body. Cancer cells do so by floating in the bloodstream and then replicating themselves in a new place. The liver, especially, provides fertile soil for metastatic spread because of its rich blood supply and the presence of humoral factors (other bodily fluids) that promote cell growth. In terms of blood flow per minute, the blood supply of the liver is second only to the lung. Liver metastases are sometimes present when the original (primary) cancer is diagnosed, or it may occur months or years after the primary tumor is removed. The majority of liver metastases present as multiple ones. Only 10% of all cases present with a single metastatic lesion. In more than three-quarters (3/4) of patients with liver metastases, both lobes of the liver are involved.