Stereotactic Injection Of MicroRNA-Expressing Lentiviruses:Hippocampus CA1 Region l Protocol Preview скачать в хорошем качестве

Stereotactic Injection Of MicroRNA-Expressing Lentiviruses:Hippocampus CA1 Region l Protocol Preview

Watch the Full Video at https://www.jove.com/v/50170/stereota.... Stereotactic Injection of MicroRNA-expressing Lentiviruses to the Mouse Hippocampus CA1 Region and Assessment of the Behavioral Outcome - a 2 minute Preview of the Experimental Protocol Shahar Barbash, Geula Hanin, Hermona Soreq The Hebrew University of Jerusalem, Department of Biological Chemistry and The Edmond & Lily Safra Center for Brain Sciences; MicroRNAs have significant roles in brain structure and function. Here we describe a method to enforce hippocampal miRNA over-expression using stereotactic injection of an engineered miRNA-expressing lentivirus. This approach can serve as a relatively rapid way to assess the in vivo effects of over-expressed miRNAs in specific brain regions. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments